Detalhe da pesquisa
1.
Phase 1 Trial of a Therapeutic Anti-Yellow Fever Virus Human Antibody.
N Engl J Med
; 383(5): 452-459, 2020 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32726531
2.
Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa.
RNA
; 25(11): 1481-1496, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31399541
3.
tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum.
Mol Syst Biol
; 14(10): e8009, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30287681
4.
Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans.
J Biol Chem
; 292(35): 14695-14703, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655767
5.
The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA.
Nucleic Acids Res
; 44(18): 8962-8975, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27365049
6.
Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa.
Nucleic Acids Res
; 44(22): 10834-10848, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683218
7.
Mycobacterial RNA isolation optimized for non-coding RNA: high fidelity isolation of 5S rRNA from Mycobacterium bovis BCG reveals novel post-transcriptional processing and a complete spectrum of modified ribonucleosides.
Nucleic Acids Res
; 43(5): e32, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25539917
8.
Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice.
J Immunol
; 191(6): 3192-9, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935193
9.
A multidimensional platform for the purification of non-coding RNA species.
Nucleic Acids Res
; 41(17): e168, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23907385
10.
2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.
PLoS Pathog
; 8(4): e1002642, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496660
11.
Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin.
Molecules
; 16(6): 5168-81, 2011 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21694680
12.
Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate.
Sci Adv
; 5(6): eaav0184, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31223645
13.
Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.
J Mol Biol
; 431(19): 3690-3705, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381898
14.
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J Med Chem
; 62(17): 7788-7805, 2019 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31442049
15.
Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors.
ACS Infect Dis
; 5(3): 326-335, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30682246
16.
Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope.
Cell Host Microbe
; 23(5): 618-627.e6, 2018 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29746833
17.
Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun
; 8(1): 1986, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29215013
18.
tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence.
Nat Commun
; 7: 13302, 2016 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27834374
19.
A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications.
Methods Enzymol
; 560: 29-71, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26253965
20.
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.
Nat Protoc
; 9(4): 828-41, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24625781